GUJARAT'S 1st TB LABORATORY
E-mail: microcaresurat@gmail.com
microcaresurat@yahoo.co.in
Telephone:  0261-2450049
 
 
 RESEARCH
We are doing collaborative research work with various diagnostic institute, university and hospitals. We also provide Training Program for infectious disease and medical microbiology for Graduate, post graduate, M.Phil, Ph.D students.​


Research Collaboration with Chemistry Department - 1

Research Collaboration with Chemistry Department - 2

Dessertation Project

Patents

PUBLICATION:

  1. Rahul V. Patel, Paresh K. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis of benzimidazolyl–1,3,4–oxadiazol–2ylthio–N–phenyl(benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents, European Journal of Medicinal Chemistry, Accepted, Elsevier, Impact Factor: 3.193.

  2. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Discovery of 2-(4-cyano-3-trifluoromethylphenylamino)-4-(4-quinazolinyloxy)-6-piperazinyl(piperidinyl)-s-triazines as potential antibacterial agents, Medicinal Chemistry Research, 2011, Accepted, Online First, Available at http://www.springerlink.com/content/u37774t837w06476/, Springer, Impact Factor: 1.058.

  3. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis, characterization and pharmacological activities of 2-[4-cyano-(3-trifluoromethyl)phenyl amino)]-4-(4-quinoline/coumarin-4-yloxy)-6- (fluoropiperazinyl)-s-triazines, Journal of Fluorine Chemistry, 2011, 132, 617-627, Elsevier, Impact Factor: 1.719.

  4. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, A new class of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl(piperidinyl)-1,3,5-triazine analogues with antimicrobial/antimycobacterial activity, Journal of Enzyme Inhibition and Medicinal Chemistry, 2011, In Press, Early Online, Available at: http://informahealthcare.com/doi/abs/10.3109/14756366.2011.592491, Informa Healthcare, Impact Factor: 1.574.

  5. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents, European Journal of Medicinal Chemistry, 2011, 46, 4354-4365, Elsevier, Impact Factor: 3.193.

  6. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis and Antimycobacterial Activity of Various 1–(8–quinolinyloxy)–3–piperazinyl(piperidinyl)–5–(4–cyano–3–trifluoromethylphenyl amino)–s–triazines, Acta Chimica Slovenica, 2011, 58, 802-810, Slovenian Chemical Society, Impact Factor: 1.01.

  7. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis of coumarin based 1,3,4–oxadiazol–2ylthio–N–phenyl (benzothiazolyl) acetamides as antimicrobial and antituberculosis agents, Medicinal Chemistry Research, 2011, Submitted, Springer, Medicinal Chemistry Research, 2012, Online First, Available at: http://www.springerlink.com/content/f1v7w55356v0nt34/. Impact Factor: 1.058.

  8. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis of potential antimicrobial/antitubercular s-triazine scaffolds endowed with quinoline and quinazoline heterocycles, International Journal of Drug Design and Discovery, 2012, 3, 730-739, Pharma Book Syndicate, Impact Factor

  9. Amit B. Patel, Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Synthesis of potential antitubercular and antimicrobial s-triazine based scaffolds via suzuki cross coupling reaction, Medicinal Chemistry Research, 2012, Accepted, Springer, Impact Factor: 1.058.

  10. Rahul V. Patel, Premlata Kumari, Dhanji P. Rajani, Kishor H. Chikhalia, Antimicrobial, antituberculosis, anticancer and anti-HIV evaluation of newer s-triazine based heterocycles, Future Medicinal Chemistry, Accepted, Future Science, Impact Factor: 1.424.

  11. Bharat Kalsariya, Galib, B.J. Patgiri, P.K. Prajapati, D.P. Rajani ,“Antibacterial Activity of Jwarahara Dashemani an Experimental Evaluation” JAMY Vol.2, No.1 Jan-Mar 2009. p65.

  12. Divyesh C. Mungraa, Manish P. Patela, Dhanji P. Rajani & Ranjan G. Patel,Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents” European Journal of Medicinal Chemistry-2011.

  13. Nayan R.Bhalodia1,V.J.Shukla2, R.N.Acharya3, D.P.Rajani , Antimicrobial screening of seed extracts of Cassia fistula Linn. - International journal of advances in pharmacy and nanotechnology - published in April issue- IJAPN / April – June 2011/ Vol. 1 / Issue. 2 / 31 – 38

  14. Nayan R.Bhalodia1, Pankaj B.Nariya, R.N.Acharya, D.P.Rajani, V.J.Shukla Antibacterial and antifungal activity of root extracts from Cassia fistula Linn. against standard pathogenic bacterial and fungal strains - International journal of pharmaceutical research and development - published in april issue - Volume. 3, Issue 02, Article No.16, April, 2011.

  15. Nayan R.Bhalodia1, Pankaj B.Nariya1, V.J.Shukla2, R.N.Acharya3, D.P.Rajani Antimicrobial screening of seed extracts of Cassia fistula Linn. Journal of pharmacology and pharmacotherapeutics - accepted and under processing

  16. Mukesh C Patel*, Nilesh N G* and D P Rajani Synthesis and characterization of some novel chromones and chromanones derivatives and its biological screening, Scholars Research Library ,Der Pharma Chemica, 2011, 3 (4):422-432.

  17. Anna Pratima G. Nikalje,*, Mudassir Pathan, Ashok S. Narute, Mangesh S.Ghodke and D. Rajani Synthesis and QSAR Study of Novel N-(3-chloro-2-oxo-4-substituted azetidin-1-yl) isonicotinamide derivatives as Anti mycobacterial Agents, Pelagia Research Library, Der Pharmacia Sinica, 2012,3 (2):229-238.

  18. Anna Pratima G. Nikalje*a, Matin Patela, Yogini Ranade and Dhanji Rajani Design and synthesis of novel N-substituted morpholino benzamide derivatives as antimicrobial agents Der Pharmacia Sinica, 2012, 3 (4):462-469.

  19. Anna Pratima G. Nikalje*, M. Pathana, M. Ghodkea and D. Rajani Synthesis of novel N-(2-substituted-4-oxothiazolidin-3-yl) isonicotinamide derivatives as anti mycobacterial agents, Der Pharmacia Sinica, 2012, 3 (4):488-493

  20. Navin B. Patela, , Amit C. Purohita, , D. P. Rajani, Rosa Moo-Pucc, Gildardo Riverad. New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: Their Synthesis and biological evaluation. European Journal of Medicinal Chemistry, Volume 62, April 2013, Pages 677–687.

  21. Navin B. Patel, Faiyazalam M. Shaikh, , Hemant R. Patel, Dhanji Rajani Synthesis of 2-pyrazolines from pyridine based chalcone by conventional and microwave techniques: Their comparison and antimicrobial studies Journal of Saudi Chemical

  22. Navin B. Patel*, Amit C Purohit, Dhanji P. Rajani.Design and synthesis of newer thiazolidinediones incorporated with pyridine and 1,3,4- oxadiazole moieties as antimicrobial agents. (International Journal of Drug Design and Discovery, 2014, 5(3), 1342-1351) ISSN: 0975-8275.

  23. Navin B. Patel*, Amit C Purohit, Dhanji P. Rajani. Newer thiazolopyrimidine based sulphonamides clubbed with benzothiazole moiety: Synthesis and biological evaluation. (Medicinal Chemistry Research, 2014, 23(7), 4789-4802) ISSN.

  24. Navin B. Patel, Faiyazalam M. Shaikh, , Hemant R. Patel, Dhanji Rajani . Synthesis andIn VitroAntimicrobial Screening of New Azetidin-2-ones of 5-Ethyl Pyridine-2-ethanol., Journal of Heterocyclic Chemistry. 2013

  25. Hitesh D. Patel,Rashmi B. Patel, Dhanji P. Rajani, Smita D. Rajani PyrazoloneThiosemicarbazone Based Metal Complexes: Physico-Chemical Study, Synthesis and Biological Activity. J. of Physical and Chemical Sciences Volume 3/Issue 2 ISSN: 2348 – 327X

  26. Hitesh D. Patel,Dayena J. Christian, Manoj N. Bhoi, Mayuri A. Borad, Dhanji P. Rajani, Smita D. Rajani Microwave Assisted Synthesis of Novel Pyrimidine Derivatives as anti-Malarial Agents. Letters in Organic ChemistryVolume: 12 First Page: 1 DOI: 10.2174/1570178612666150423215041

  27. Hitesh D. Patel,Saavani M. Divatia,Dhanji P. Rajani,Smita D. Rajani Novel thiosemicarbazones derivatives containing benzimidazole moiety: Green synthesis and anti-malarial activity, Arabian Journal of Chemistry 2014, DOI: 10.1016/j.arabjc.2014.09.007 ISSN, 1878-5352.

  28. Hitesh D. Patel, Shraddha M. Prajapati, Rajesh H. Vekariya, Kinjal D. Patel, Shyamali N. Panchal, Dhanji P. Rajani, Smita D. Rajani Synthesis and in vitro antibacterial and antifungal evaluation of quinoline analogue azetidin and thiazolidin derivatives. International Letters of Chemistry, Physics and Astronomy, 2014, 20 (2), 195-210.

  29. Hitesh D. Patel, Dayena J. Christain, Manoj N. Bhoi, Mayuri A. Borad, Dhanji P. Rajani, Smita D. Rajani Microwave assisted synthesis and in vitro anti-malarial screening of novel pyrimidine derivatives. WJPPS 2014, 3, 1955-1971.

  30. Hitesh D. Patel, Mayuri A. Borad, Manoj N. Bhoi, Dhanji P. Rajani, Smita D. Rajani Synthesis and antimicrobial activities of 2-(4-substituted phenyl)-1,10b dihydrospiro [benzo[e]pyrazolo[1,5-c][1,3]oxaz ine-5, 3’-indolin]-2'-one derivative from isatin. WJPPS 2014, 3, 805-821.

  31. Smita D Rajani, Pratibha B Desai, Dhanji P Rajani Anti-mycobacterial activity of garlic (Allium sativum) against multi-drug resistant and reference strain of Mycobacterium tuberculosis.IJAS 2015 1(13): 767-770.

  32. Smita D Rajani, Pratibha B Desai, Dhanji P Rajani Evaluation of the Performance of Nitrate Reductase Assay for Rapid Drug-Susceptibility Testing of Mycobacterium Tuberculosis in South Gujarat Region.IJSR 2015 vol.4 Issue 10. 967-971.